Clinical Trials at PeeTu

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Clinical Cancer Trials

Cancer type Name in English
Relapsed/Refractory ALL, AML Kliiniset tutkimukset -avoinna ISAKIDS  - Lohi
Isatuximab in Combination with Chemotherapy in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
ALL, relapsed Kliiniset tutkimukset -avoinna IntReALL HR 2010 -Lohi
International study for treatment of childhood relapsed ALL High risk group
High Risk Neuroblastoma Kliiniset tutkimukset - ei uusia potilaita High risk neuroblastoma study 1.8 of SIOP-Europe (SIOPEN)   - Palmu
Acute myeloid leukaemia (AML) Kliiniset tutkimukset - ei uusia potilaita NOPHO-DBH-2012 - Arola
Research study for treatment of children and adolescent with acute myeloid leukaemia 0-18 years
Ewing sarcoma, relapsed Kliiniset tutkimukset -avoinna rEECur - Arola
International randomised controlled trial of Chemotherapy for the treatment of recurrent and primary refractory ewing sarcoma
Medulloblastoma

 
Kliiniset tutkimukset -avoinna PNET 5 MB - Arola
An international prospective study on clinically standard-risk medulloblastoma in children older than 3 to 5 years with low-risk biological profile(PNET 5 MB-LR) or average-risk bilogical profile (PNET 5 MB-SR)
Leukemia Kliiniset tutkimukset -avoinna Leukemia biology - Lohi
Study on the biology and genomics of acute leukemia in childhood
B-cell lymphoma and leukemia Kliiniset tutkimukset -avoinna B-NHL 2013 - Raittinen
Treatment protocol for mature agressive B-cell lymphoma and leukemia in children and adolescents
High and Low Grade Glioma (HGG, LGG) Kliiniset tutkimukset -avoinna Tadpole-G - Lohi
Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive Low Grade Glioma (LGG) or relapsed or refractory High Grade Glioma (HGG)
Hodgin lymphoma Kliiniset tutkimukset -avoinna EuroNet PHL-C2 - Raittinen
International, multicentre, randomised controlled trial with the aims to reduce the indication for radiotherapy in newly diagnosed patients with classical Hodgkin lymphoma without compromising cure rates and to investigate a chemotherapy intensification randomisation in intermediate and advanced classical Hodgkin lymphoma to compensate for reduction in radiotherapy.
Non-Hodgin-lymphoma Kliiniset tutkimukset -avoinna CNS HNL Flow study - Raittinen
Relapsed Malignancies in Childhood Kliiniset tutkimukset -avoinna INFORM Registry - Lohi
Individualized Therapy for Relapsed Malignancies in Childhood
Osteosarcoma Kliiniset tutkimukset -avoinna OLIE - Lohi
A Multicenter, Open-label, Randomized Phase 2 Study to Compare the Efficacy and Safety of Lenvatinib in Combination with Ifosfamide and Etoposide versus Ifosfamide and Etoposide in Children, Adolescents and Young Adults with Relapsed or Refractory Osteosarcoma
Relapsed/Refractory cancer Kliiniset tutkimukset -avoinna

NOPHOmatch  - Sauli Palmu
Matching relapsed/refractory cancers with more phase 1-2 clinical trials.

Other Trials

Diabetes Kliiniset tutkimukset - ei uusia potilaita Tefa -Palmu
A randomized investigator-initiated study to determine the effect of gluten free diet on beta-cell function and glucose metabolism in subjects positive for one or several islet autoantibodies
Influenza Kliiniset tutkimukset -avoinna MINIstone - Palmu
A multicenter, single-arm, open label sudy to assess the safety, pharmacokinetics  and efficacy of baloxavir marboxil in otherwise healthy pediatric patients from birth to < 1 year with influenza-like symptoms
Chronic Migraine Kliiniset tutkimukset -avoinna

Space - Raisio
Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy, Safety, and Tolerability of Subcutaneous Administration of Fremanezumab Versus Placebo for the Preventive Treatment of Chronic Migraine in Pediatric Patients 6 to 17 Years of Age

Episodic Migraine Kliiniset tutkimukset -avoinna

Space - Raisio
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy, Safety, and Tolerability of Subcutaneous Administration of Fremanezumab Versus Placebo for the Preventive Treatment of Episodic Migraine in Pediatric Patients 6 to 17 Years of Age

Episodic and Chronic Migraine Kliiniset tutkimukset -avoinna

Space - Raisio
A Multicenter, Open-Label Study Evaluating the Long-Term Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of Fremanezumab for the Preventive Treatment of Episodic and Chronic Migraine in Pediatric Patients 6 to 17 Years of Age

Acute wheezing Kliiniset tutkimukset -avoinna

Chamber - Palmu
Comparing the efficacy of two valved holding chambers for bronchodilator administration in 0.5-4 years old children with acute wheezing – a randomized clinical trial

Preterm Kliiniset tutkimukset -avoinna

TREOCAPA - Tammela
Prophylactic treatment of the ductus arteriosus in preterm infants by acetaminophen

Chronic kidney disease                        

Kliiniset tutkimukset -avoinna FIONA - Palmu
A 6-month multicenter, randomized, double-blind, placebo-controlled study to  and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children, 6 months to <18 years of age, with chronic kidney disease and proteinuria         

Fibrosing Interstitial Lung disease 

Kliiniset tutkimukset -avoinna InPedILD™-ON - Palmu
open-label trial of the long-term safety and tolerability of nintedanib per os, on top of standard of Lung disease care, over at least 2 years, in children and adolescents with clinically significant fibrosing Interstitial Lung Disease
 
Relaxation Kliiniset tutkimukset -avoinna

Virtual reality - Palmu
Virtual reality meditated deep breathing and relaxation training in pediatric care for children

Kawasaki Disease Icon - not yet opened for inclusion

KD-CAAP - Palmu
Kawasaki Disease Coronary Artery Aneurysm Prevention trial

Ulcerative colitis

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OVATION - Hiltunen
Open-label induction and maintenance study of oral CP-690,550 (Tofacitinib) in children with moderately to severely active ulcerative colitis